Published December 7, 2011 | Version v1
Publication Open

Metallic ions as therapeutic agents in tissue engineering scaffolds: an overview of their biological applications and strategies for new developments

Creators

  • 1. Consejo Nacional de Investigaciones Científicas y Técnicas
  • 2. University of Buenos Aires
  • 3. Friedrich-Alexander-Universität Erlangen-Nürnberg

Description

This article provides an overview on the application of metallic ions in the fields of regenerative medicine and tissue engineering, focusing on their therapeutic applications and the need to design strategies for controlling the release of loaded ions from biomaterial scaffolds. A detailed summary of relevant metallic ions with potential use in tissue engineering approaches is presented. Remaining challenges in the field and directions for future research efforts with focus on the key variables needed to be taken into account when considering the controlled release of metallic ions in tissue engineering therapeutics are also highlighted.

⚠️ This is an automatic machine translation with an accuracy of 90-95%

Translated Description (Arabic)

تقدم هذه المقالة لمحة عامة عن تطبيق الأيونات المعدنية في مجالات الطب التجديدي وهندسة الأنسجة، مع التركيز على تطبيقاتها العلاجية والحاجة إلى تصميم استراتيجيات للتحكم في إطلاق الأيونات المحملة من سقالات المواد الحيوية. يتم تقديم ملخص مفصل للأيونات المعدنية ذات الصلة مع الاستخدام المحتمل في مناهج هندسة الأنسجة. كما تم تسليط الضوء على التحديات المتبقية في هذا المجال والتوجهات للجهود البحثية المستقبلية مع التركيز على المتغيرات الرئيسية التي يجب أخذها في الاعتبار عند النظر في الإطلاق الخاضع للرقابة للأيونات المعدنية في علاجات هندسة الأنسجة.

Translated Description (French)

Cet article donne un aperçu de l'application des ions métalliques dans les domaines de la médecine régénérative et de l'ingénierie tissulaire, en mettant l'accent sur leurs applications thérapeutiques et la nécessité de concevoir des stratégies pour contrôler la libération d'ions chargés à partir d'échafaudages biomatériaux. Un résumé détaillé des ions métalliques pertinents pouvant être utilisés dans les approches d'ingénierie tissulaire est présenté. Les défis restants dans le domaine et les orientations pour les futurs efforts de recherche en mettant l'accent sur les variables clés devant être prises en compte lors de l'examen de la libération contrôlée d'ions métalliques dans les thérapies de génie tissulaire sont également mis en évidence.

Translated Description (Spanish)

Este artículo proporciona una visión general sobre la aplicación de iones metálicos en los campos de la medicina regenerativa y la ingeniería de tejidos, centrándose en sus aplicaciones terapéuticas y la necesidad de diseñar estrategias para controlar la liberación de iones cargados de los andamios de biomateriales. Se presenta un resumen detallado de iones metálicos relevantes con uso potencial en enfoques de ingeniería de tejidos. También se destacan los desafíos restantes en el campo y las direcciones para futuros esfuerzos de investigación con un enfoque en las variables clave que deben tenerse en cuenta al considerar la liberación controlada de iones metálicos en la terapéutica de ingeniería de tejidos.

Files

rsif.2011.0611.pdf

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Additional details

Additional titles

Translated title (Arabic)
الأيونات المعدنية كعوامل علاجية في سقالات هندسة الأنسجة: نظرة عامة على تطبيقاتها البيولوجية واستراتيجياتها للتطورات الجديدة
Translated title (French)
Les ions métalliques comme agents thérapeutiques dans les échafaudages d'ingénierie tissulaire : un aperçu de leurs applications biologiques et des stratégies pour de nouveaux développements
Translated title (Spanish)
Iones metálicos como agentes terapéuticos en andamios de ingeniería de tejidos: una visión general de sus aplicaciones biológicas y estrategias para nuevos desarrollos

Identifiers

Other
https://openalex.org/W2104026218
DOI
10.1098/rsif.2011.0611

Is supplement to
https://openalex.org/W4381058834 (Other)
https://openalex.org/W3215530055 (Other)
https://openalex.org/W3171090766 (Other)
https://openalex.org/W3147118347 (Other)
https://openalex.org/W3014163099 (Other)
https://openalex.org/W2889165517 (Other)
https://openalex.org/W2545305293 (Other)
https://openalex.org/W2435286860 (Other)
https://openalex.org/W2339150871 (Other)
https://openalex.org/W2287501499 (Other)

GreSIS Basics Section

Is Global South Knowledge
Yes
Country
Argentina

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