Published August 13, 2014
| Version v1
Publication
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Diagnosis of leishmaniasis
Creators
- 1. Sohag University
- 2. Hospital Universitario Virgen de las Nieves
- 3. Universidad de Granada
Description
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical (not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immunoinflammatory responses. Visceral leishmaniasis causes high morbidity and mortality in the developing world. Reliable laboratory methods become mandatory for accurate diagnosis, especially in immunocompromised patients such as those infected with HIV. In this article, we review the current state of the diagnostic tools for leishmaniasis, especially the serological test.
Translated Descriptions
⚠️
This is an automatic machine translation with an accuracy of 90-95%
Translated Description (Arabic)
داء الليشمانيات هو متلازمة غير متجانسة سريريًا تسببها طفيليات البروتوزوان داخل الخلايا من جينات الليشمانيا. يشمل الطيف السريري لداء الليشمانيات العدوى دون السريرية (غير الظاهرة)، الموضعية (الآفة الجلدية)، والمنتشرة (الجلدية، المخاطية الجلدية، والحشوية). يعتمد هذا الطيف من المظاهر على الحالة المناعية للمضيف، وعلى الطفيلي، وعلى الاستجابات الالتهابية المناعية. يتسبب داء الليشمانيات الحشوي في ارتفاع معدلات المراضة والوفيات في العالم النامي. تصبح الطرق المختبرية الموثوقة إلزامية للتشخيص الدقيق، خاصة في المرضى الذين يعانون من نقص المناعة مثل المصابين بفيروس نقص المناعة البشرية. في هذه المقالة، نستعرض الحالة الراهنة لأدوات تشخيص داء الليشمانيات، وخاصة الاختبار المصلي.Translated Description (English)
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genes Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical (not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immunoinflammatory responses. Visceral leishmaniasis causes high morbidity and mortality in the developing world. Reliable laboratory methods become mandatory for accurate diagnosis, especially in immunocompromised patients such as those infected with HIV. In this article, we review the current state of the diagnostic tools for leishmaniasis, especially the serological test.Translated Description (French)
La leishmaniose est un syndrome cliniquement hétérogène causé par des protozoaires intracellulaires parasites des gènes Leishmania. Le spectre clinique de la leishmaniose englobe les infections subcliniques (non apparentes), localisées (lésions cutanées) et disséminées (cutanées, mucocutanées et viscérales). Ce spectre de manifestations dépend de l'état immunitaire de l'hôte, du parasite et des réponses immuno-inflammatoires. La leishmaniose viscérale provoque une morbidité et une mortalité élevées dans les pays en développement. Des méthodes de laboratoire fiables deviennent obligatoires pour un diagnostic précis, en particulier chez les patients immunodéprimés tels que ceux infectés par le VIH. Dans cet article, nous passons en revue l'état actuel des outils de diagnostic de la leishmaniose, en particulier le test sérologique.Translated Description (Spanish)
La leishmaniasis es un síndrome clínicamente heterogéneo causado por parásitos protozoarios intracelulares de los genes Leishmania. El espectro clínico de la leishmaniasis abarca la infección subclínica (no aparente), localizada (lesión cutánea) y diseminada (cutánea, mucocutánea y visceral). Este espectro de manifestaciones depende del estado inmunitario del huésped, del parásito y de las respuestas inmunoinflamatorias. La leishmaniasis visceral causa una alta morbilidad y mortalidad en el mundo en desarrollo. Los métodos de laboratorio fiables se vuelven obligatorios para un diagnóstico preciso, especialmente en pacientes inmunocomprometidos como los infectados por el VIH. En este artículo, revisamos el estado actual de las herramientas de diagnóstico de la leishmaniasis, especialmente la prueba serológica.Files
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Additional details
Additional titles
- Translated title (Arabic)
- تشخيص داء الليشمانيات
- Translated title (English)
- Diagnosis of leishmaniasis
- Translated title (French)
- Diagnostic de la leishmaniose
- Translated title (Spanish)
- Diagnóstico de la leishmaniasis
Identifiers
- Other
- https://openalex.org/W2137286214
- DOI
- 10.3855/jidc.4310
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