Published February 17, 2021
| Version v1
Publication
Open
Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity
Creators
- 1. National University of General San Martín
- 2. Consejo Nacional de Investigaciones Científicas y Técnicas
Description
A common strategy to identify new antiparasitic agents is the targeting of proteases, due to their essential contributions to parasite growth and development. Metacaspases (MCAs) are cysteine proteases present in fungi, protozoa, and plants.
Translated Descriptions
⚠️
This is an automatic machine translation with an accuracy of 90-95%
Translated Description (Arabic)
تتمثل الإستراتيجية الشائعة لتحديد العوامل الجديدة المضادة للطفيليات في استهداف البروتياز، نظرًا لمساهماتها الأساسية في نمو الطفيليات وتطورها. Metacaspases (MCAS) هي بروتياز السيستين الموجود في الفطريات والبروتوزوا والنباتات.Translated Description (French)
Une stratégie commune pour identifier de nouveaux agents antiparasitaires est le ciblage des protéases, en raison de leurs contributions essentielles à la croissance et au développement des parasites. Les métacaspases (MCAS) sont des cystéine protéases présentes dans les champignons, les protozoaires et les plantes.Translated Description (Spanish)
Una estrategia común para identificar nuevos agentes antiparasitarios es el direccionamiento de las proteasas, debido a sus contribuciones esenciales al crecimiento y desarrollo del parásito. Las metacaspasas (MCA) son cisteína proteasas presentes en hongos, protozoos y plantas.Files
CONICET_Digital_Nro.87d43771-0137-412a-bbfc-4c11a2420dfc_E.pdf.pdf
Files
(2.6 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:46a6ee6edf2050cf8efafa3551371273
|
2.6 MB | Preview Download |
Additional details
Additional titles
- Translated title (Arabic)
- فحص وتحديد مثبطات Metacaspase: تقييم آلية التثبيط ونشاط مبيد المثقبيات
- Translated title (French)
- Dépistage et identification des inhibiteurs des métacaspases : évaluation du mécanisme d'inhibition et de l'activité trypanocide
- Translated title (Spanish)
- Detección e identificación de inhibidores de metacaspasas: evaluación del mecanismo de inhibición y la actividad tripanocida
Identifiers
- Other
- https://openalex.org/W3111974468
- DOI
- 10.1128/aac.01330-20
References
- https://openalex.org/W1563650227
- https://openalex.org/W1964789691
- https://openalex.org/W1980516761
- https://openalex.org/W1987328222
- https://openalex.org/W1987546203
- https://openalex.org/W1991001144
- https://openalex.org/W1992669214
- https://openalex.org/W1997514006
- https://openalex.org/W2008880656
- https://openalex.org/W2035555452
- https://openalex.org/W2042175198
- https://openalex.org/W2044111397
- https://openalex.org/W2064804935
- https://openalex.org/W2064881809
- https://openalex.org/W2075635047
- https://openalex.org/W2077115594
- https://openalex.org/W2077451644
- https://openalex.org/W2078027213
- https://openalex.org/W2078611842
- https://openalex.org/W2082792211
- https://openalex.org/W2089966673
- https://openalex.org/W2090286595
- https://openalex.org/W2101444644
- https://openalex.org/W2105092700
- https://openalex.org/W2120662385
- https://openalex.org/W2122717342
- https://openalex.org/W2123509214
- https://openalex.org/W2124072633
- https://openalex.org/W2338545708
- https://openalex.org/W2734965201
- https://openalex.org/W2755085907
- https://openalex.org/W2767153097
- https://openalex.org/W2793386277
- https://openalex.org/W2800884582
- https://openalex.org/W2893685952
- https://openalex.org/W2920936824
- https://openalex.org/W2953028643
- https://openalex.org/W2960754223
- https://openalex.org/W2964168407
- https://openalex.org/W2970692502
- https://openalex.org/W3010258033