Published July 5, 2019 | Version v1
Publication Open

Bioactıve Glass‐Polymer Nanocomposites for Bone Tıssue Regeneration Applicatıons: A Revıew

Creators

  • 1. Istanbul Technical University
  • 2. Friedrich-Alexander-Universität Erlangen-Nürnberg
  • 3. Tun Hussein Onn University of Malaysia
  • 4. University of Aveiro

Description

Nanosized bioactive glass (NBG) particles are attractive materials for bone repair because of their ability to enhance bone formation and to chemically bond to the surrounding bone tissue. In recent years, composites of biopolymers and NBG particles have been developed for bone tissue engineering due to their increased bioactivity, biocompatibility, and biodegradability. In this paper, the authors review current knowledge regarding polymer/NBG composites, including nanoscale‐related features and ion‐release effects of bioactive glass (BG) with respect to osteogenic and angiogenic responses in vivo and in vitro; the authors also focus on the techniques used to fabricate these nanocomposites. Additionally, this review discusses recent developments in the use of nanocomposites for tissue engineering and represents a literature update, as well an expansion, of previously published articles on this topic.

⚠️ This is an automatic machine translation with an accuracy of 90-95%

Translated Description (Arabic)

جزيئات الزجاج النشط بيولوجيًا نانويًا (NBG) هي مواد جذابة لإصلاح العظام بسبب قدرتها على تعزيز تكوين العظام والارتباط كيميائيًا بالأنسجة العظمية المحيطة. في السنوات الأخيرة، تم تطوير مركبات البوليمرات الحيوية وجسيمات NBG لهندسة الأنسجة العظمية بسبب زيادة نشاطها الحيوي وتوافقها الحيوي وقابليتها للتحلل الحيوي. في هذه الورقة، يستعرض المؤلفون المعرفة الحالية فيما يتعلق بمركبات البوليمر/NBG، بما في ذلك الميزات المتعلقةبالنانو وتأثيرات إطلاق الأيونات للزجاج النشط بيولوجيًا (BG) فيما يتعلق بالاستجابات العظمية والأوعية الدموية في الجسم الحي وفي المختبر ؛ يركز المؤلفون أيضًا على التقنيات المستخدمة لتصنيع هذه المركبات النانوية. بالإضافة إلى ذلك، تناقش هذه المراجعة التطورات الأخيرة في استخدام المركبات النانوية في هندسة الأنسجة وتمثل تحديثًا للأدبيات، بالإضافة إلى توسيع للمقالات المنشورة سابقًا حول هذا الموضوع.

Translated Description (French)

Les particules de verre bioactif (NBG) de taille nanométrique sont des matériaux attrayants pour la réparation osseuse en raison de leur capacité à améliorer la formation osseuse et à se lier chimiquement au tissu osseux environnant. Ces dernières années, des composites de biopolymères et de particules de NBG ont été développés pour l'ingénierie du tissu osseux en raison de leur bioactivité, de leur biocompatibilité et de leur biodégradabilité accrues. Dans cet article, les auteurs passent en revue les connaissances actuelles concernant les composites polymère/NBG, y compris les caractéristiques liées à l'échelle nanométrique et les effets de libération d'ions du verre bioactif (BG) en ce qui concerne les réponses ostéogéniques et angiogéniques in vivo et in vitro ; les auteurs se concentrent également sur les techniques utilisées pour fabriquer ces nanocomposites. En outre, cette revue traite des développements récents dans l'utilisation des nanocomposites pour l'ingénierie tissulaire et représente une mise à jour de la littérature, ainsi qu'une expansion, des articles précédemment publiés sur ce sujet.

Translated Description (Spanish)

Las partículas de vidrio bioactivo nanométrico (NBG) son materiales atractivos para la reparación ósea debido a su capacidad para mejorar la formación ósea y unirse químicamente al tejido óseo circundante. En los últimos años, se han desarrollado compuestos de biopolímeros y partículas de NBG para la ingeniería de tejidos óseos debido a su mayor bioactividad, biocompatibilidad y biodegradabilidad. En este artículo, los autores revisan el conocimiento actual con respecto a los compuestos de polímero/NBG, incluidas las características relacionadascon la nanoescala y los efectos de liberación de iones del vidrio bioactivo (BG) con respecto a las respuestas osteogénicas y angiogénicas in vivo e in vitro; los autores también se centran en las técnicas utilizadas para fabricar estos nanocompuestos. Además, esta revisión analiza los desarrollos recientes en el uso de nanocompuestos para la ingeniería de tejidos y representa una actualización de la literatura, así como una expansión de los artículos publicados anteriormente sobre este tema.

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Additional details

Additional titles

Translated title (Arabic)
Bioactıve Glass-Polymer Nanocomposites for Bone Tıssue تجديد التطبيقات: A Revıew
Translated title (French)
Nanocomposites de verre‐polymère Bioactıve pour la régénération des tissus osseux Applicatıons : A Revıew
Translated title (Spanish)
Bioactıve Glass‐Polymer Nanocomposites for Bone Tıssue Regeneration Applicatıons: A Revıew

Identifiers

Other
https://openalex.org/W2954311525
DOI
10.1002/adem.201900287

Is supplement to
https://openalex.org/W2561756220 (Other)
https://openalex.org/W2550159186 (Other)
https://openalex.org/W2414282704 (Other)
https://openalex.org/W2393655250 (Other)
https://openalex.org/W2393417063 (Other)
https://openalex.org/W2367291566 (Other)
https://openalex.org/W2365560514 (Other)
https://openalex.org/W2350003174 (Other)
https://openalex.org/W2184772883 (Other)
https://openalex.org/W1964675209 (Other)

GreSIS Basics Section

Is Global South Knowledge
Yes
Country
Turkey

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