Published January 10, 2022 | Version v1
Publication Open

Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge

Creators

  • 1. Zewail City of Science and Technology
  • 2. Beni-Suef University

Description

The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It acts as a highly biocompatible natural scaffold and as a source of several types of stem cells and potent growth factors. It also serves as an effective nano-reservoir for drug delivery, thanks to its high entrapment properties. Over the past century, the use of the Amnio-M in the clinic has evolved from a simple sheet for topical applications for skin and corneal repair into more advanced forms, such as micronized dehydrated membrane, amniotic cytokine extract, and solubilized powder injections to regenerate muscles, cartilage, and tendons. This review highlights the development of the Amnio-M over the years and the implication of new and emerging nanotechnology to support expanding its use for tissue engineering and clinical applications.

⚠️ This is an automatic machine translation with an accuracy of 90-95%

Translated Description (Arabic)

الغشاء الأمنيوسي (Amnio - M) له تطبيقات مختلفة في الطب التجديدي. وهو بمثابة سقالة طبيعية متوافقة حيويا للغاية وكمصدر لعدة أنواع من الخلايا الجذعية وعوامل النمو القوية. كما أنه بمثابة خزان نانو فعال لتوصيل الأدوية، وذلك بفضل خصائصه العالية في الاحتباس. على مدى القرن الماضي، تطور استخدام Amnio - M في العيادة من ورقة بسيطة للتطبيقات الموضعية لإصلاح الجلد والقرنية إلى أشكال أكثر تقدمًا، مثل الغشاء المجفف المجهري، ومستخلص السيتوكين الأمنيوسي، وحقن المسحوق المذاب لتجديد العضلات والغضاريف والأوتار. تسلط هذه المراجعة الضوء على تطور Amnio - M على مر السنين وتأثير تكنولوجيا النانو الجديدة والناشئة لدعم توسيع استخدامها لهندسة الأنسجة والتطبيقات السريرية.

Translated Description (French)

La membrane amniotique (Amnio-M) a diverses applications en médecine régénérative. Il agit comme un échafaudage naturel hautement biocompatible et comme une source de plusieurs types de cellules souches et de facteurs de croissance puissants. Il sert également de nano-réservoir efficace pour l'administration de médicaments, grâce à ses propriétés de piégeage élevées. Au cours du siècle dernier, l'utilisation de l'Amnio-M en clinique est passée d'une simple feuille pour des applications topiques pour la réparation de la peau et de la cornée à des formes plus avancées, telles que la membrane déshydratée micronisée, l'extrait de cytokine amniotique et les injections de poudre solubilisée pour régénérer les muscles, le cartilage et les tendons. Cette revue met en évidence le développement de l'Amnio-M au fil des ans et l'implication des nanotechnologies nouvelles et émergentes pour soutenir l'expansion de son utilisation pour l'ingénierie tissulaire et les applications cliniques.

Translated Description (Spanish)

La membrana amniótica (Amnio-M) tiene diversas aplicaciones en medicina regenerativa. Actúa como un andamio natural altamente biocompatible y como fuente de varios tipos de células madre y potentes factores de crecimiento. También sirve como un nanorreservorio eficaz para la administración de fármacos, gracias a sus altas propiedades de atrapamiento. Durante el siglo pasado, el uso del Amnio-M en la clínica ha evolucionado de una simple lámina para aplicaciones tópicas para la reparación de la piel y la córnea a formas más avanzadas, como la membrana deshidratada micronizada, el extracto de citocinas amnióticas y las inyecciones de polvo solubilizado para regenerar músculos, cartílagos y tendones. Esta revisión destaca el desarrollo del Amnio-M a lo largo de los años y la implicación de la nanotecnología nueva y emergente para apoyar la expansión de su uso para la ingeniería de tejidos y las aplicaciones clínicas.

Files

s13287-021-02684-0.pdf

Files (2.4 MB)

⚠️ Please wait a few minutes before your translated files are ready ⚠️ Note: Some files might be protected thus translations might not work.
Name Size Download all
md5:680cbd9274a2fd686716837f979efb65
2.4 MB
Preview Download

Additional details

Additional titles

Translated title (Arabic)
تطبيقات الغشاء الأمنيوسي في هندسة الأنسجة وتجديدها: تحدي المائة عام
Translated title (French)
Applications de la membrane amniotique dans l'ingénierie tissulaire et la régénération : le défi centenaire
Translated title (Spanish)
Aplicaciones de la membrana amniótica en la ingeniería y regeneración de tejidos: el desafío de los cien años

Identifiers

Other
https://openalex.org/W4206420021
DOI
10.1186/s13287-021-02684-0

Is supplement to
https://openalex.org/W922543731 (Other)
https://openalex.org/W3215530055 (Other)
https://openalex.org/W3196863326 (Other)
https://openalex.org/W3014163099 (Other)
https://openalex.org/W3003069570 (Other)
https://openalex.org/W2626164717 (Other)
https://openalex.org/W2478420051 (Other)
https://openalex.org/W2435286860 (Other)
https://openalex.org/W2412922490 (Other)
https://openalex.org/W2387757681 (Other)

GreSIS Basics Section

Is Global South Knowledge
Yes
Country
Egypt

References

  • https://openalex.org/W1510329651
  • https://openalex.org/W1517811547
  • https://openalex.org/W1526429212
  • https://openalex.org/W154531295
  • https://openalex.org/W1705586769
  • https://openalex.org/W1820096065
  • https://openalex.org/W1931307788
  • https://openalex.org/W1963589532
  • https://openalex.org/W1964847767
  • https://openalex.org/W1966556266
  • https://openalex.org/W1968667554
  • https://openalex.org/W1968806250
  • https://openalex.org/W1974558442
  • https://openalex.org/W1976802994
  • https://openalex.org/W1977534284
  • https://openalex.org/W1978423599
  • https://openalex.org/W1981623948
  • https://openalex.org/W1982316191
  • https://openalex.org/W1984560751
  • https://openalex.org/W1986860180
  • https://openalex.org/W1987705942
  • https://openalex.org/W1988349464
  • https://openalex.org/W1988787256
  • https://openalex.org/W1989808777
  • https://openalex.org/W1992970384
  • https://openalex.org/W1994452827
  • https://openalex.org/W1994661247
  • https://openalex.org/W1994667536
  • https://openalex.org/W1995143153
  • https://openalex.org/W1997660220
  • https://openalex.org/W1998469527
  • https://openalex.org/W1999568665
  • https://openalex.org/W1999806476
  • https://openalex.org/W2003351132
  • https://openalex.org/W2004026324
  • https://openalex.org/W2010233175
  • https://openalex.org/W2012377108
  • https://openalex.org/W2012852518
  • https://openalex.org/W2015524556
  • https://openalex.org/W2017655153
  • https://openalex.org/W2019072415
  • https://openalex.org/W2020516762
  • https://openalex.org/W2020722287
  • https://openalex.org/W2023337235
  • https://openalex.org/W2023427736
  • https://openalex.org/W2024431976
  • https://openalex.org/W2026738954
  • https://openalex.org/W2027540026
  • https://openalex.org/W2030393192
  • https://openalex.org/W2032611754
  • https://openalex.org/W2033389274
  • https://openalex.org/W2033458853
  • https://openalex.org/W2038113465
  • https://openalex.org/W2039685709
  • https://openalex.org/W2040091260
  • https://openalex.org/W2042862142
  • https://openalex.org/W2043050808
  • https://openalex.org/W2043897987
  • https://openalex.org/W2044475547
  • https://openalex.org/W2048489410
  • https://openalex.org/W2052181084
  • https://openalex.org/W2053653008
  • https://openalex.org/W2054566768
  • https://openalex.org/W2056158804
  • https://openalex.org/W2056292710
  • https://openalex.org/W2056328978
  • https://openalex.org/W2056404918
  • https://openalex.org/W2060191250
  • https://openalex.org/W2061307460
  • https://openalex.org/W2062101834
  • https://openalex.org/W2064297038
  • https://openalex.org/W2066307478
  • https://openalex.org/W2068716971
  • https://openalex.org/W2068727569
  • https://openalex.org/W2071110385
  • https://openalex.org/W2074254399
  • https://openalex.org/W2074532762
  • https://openalex.org/W2077808219
  • https://openalex.org/W2082437196
  • https://openalex.org/W2082490993
  • https://openalex.org/W2085292554
  • https://openalex.org/W2085803277
  • https://openalex.org/W2087390755
  • https://openalex.org/W2087747454
  • https://openalex.org/W2088761756
  • https://openalex.org/W2093706858
  • https://openalex.org/W2096171314
  • https://openalex.org/W2098435453
  • https://openalex.org/W2106647511
  • https://openalex.org/W2109540032
  • https://openalex.org/W2116484695
  • https://openalex.org/W2117611251
  • https://openalex.org/W2118952936
  • https://openalex.org/W2134148509
  • https://openalex.org/W2134720588
  • https://openalex.org/W2144543455
  • https://openalex.org/W2144545117
  • https://openalex.org/W2145820173
  • https://openalex.org/W2148097737
  • https://openalex.org/W2150384215
  • https://openalex.org/W2152451347
  • https://openalex.org/W2154607675
  • https://openalex.org/W2164848082
  • https://openalex.org/W2165438231
  • https://openalex.org/W2172802127
  • https://openalex.org/W2185333371
  • https://openalex.org/W2187234167
  • https://openalex.org/W2237111586
  • https://openalex.org/W2260259400
  • https://openalex.org/W2276979229
  • https://openalex.org/W2295401898
  • https://openalex.org/W2314102177
  • https://openalex.org/W2323414559
  • https://openalex.org/W2401907080
  • https://openalex.org/W2406453633
  • https://openalex.org/W2417309232
  • https://openalex.org/W2473461569
  • https://openalex.org/W2520360513
  • https://openalex.org/W2539050959
  • https://openalex.org/W2559778093
  • https://openalex.org/W2559968356
  • https://openalex.org/W2560917706
  • https://openalex.org/W2592152681
  • https://openalex.org/W2592412503
  • https://openalex.org/W2606077693
  • https://openalex.org/W2607564237
  • https://openalex.org/W2626907686
  • https://openalex.org/W2628574358
  • https://openalex.org/W2741091826
  • https://openalex.org/W2742971121
  • https://openalex.org/W2760173530
  • https://openalex.org/W2761845696
  • https://openalex.org/W2767280943
  • https://openalex.org/W2769786321
  • https://openalex.org/W2774336721
  • https://openalex.org/W2781628997
  • https://openalex.org/W2789259361
  • https://openalex.org/W2790175787
  • https://openalex.org/W2790255586
  • https://openalex.org/W2790436657
  • https://openalex.org/W2790602462
  • https://openalex.org/W2793853619
  • https://openalex.org/W2793858243
  • https://openalex.org/W2796449908
  • https://openalex.org/W2799539101
  • https://openalex.org/W2807992373
  • https://openalex.org/W2882547885
  • https://openalex.org/W2886848991
  • https://openalex.org/W2892264958
  • https://openalex.org/W2893480081
  • https://openalex.org/W2896329764
  • https://openalex.org/W2898886337
  • https://openalex.org/W2900746210
  • https://openalex.org/W2914115792
  • https://openalex.org/W2921078719
  • https://openalex.org/W2924533850
  • https://openalex.org/W2929761679
  • https://openalex.org/W2941908346
  • https://openalex.org/W2943251714
  • https://openalex.org/W2944571965
  • https://openalex.org/W2945072781
  • https://openalex.org/W2945895590
  • https://openalex.org/W2948689994
  • https://openalex.org/W2951465543
  • https://openalex.org/W2953688031
  • https://openalex.org/W2954922122
  • https://openalex.org/W2956124744
  • https://openalex.org/W2963927727
  • https://openalex.org/W2972621001
  • https://openalex.org/W2983650814
  • https://openalex.org/W2990418437
  • https://openalex.org/W3022829733
  • https://openalex.org/W3025422121
  • https://openalex.org/W3026434627
  • https://openalex.org/W3081329611
  • https://openalex.org/W3083432709
  • https://openalex.org/W3093771364
  • https://openalex.org/W3110459867
  • https://openalex.org/W3119795194
  • https://openalex.org/W3135799839
  • https://openalex.org/W3140516373
  • https://openalex.org/W3150758852
  • https://openalex.org/W3154780234
  • https://openalex.org/W3202786230
  • https://openalex.org/W4211233744
  • https://openalex.org/W90204503
  • https://openalex.org/W98755530