Published May 1, 2024 | Version v1
Publication

Titanium-Based alloys and composites for orthopedic implants Applications: A comprehensive review

  • 1. Zagazig University
  • 2. University of California, Los Angeles
  • 3. Tanta University
  • 4. University of Oulu
  • 5. Helwan University
  • 6. Imam Mohammad ibn Saud Islamic University

Description

The increasing demand for orthopedic implants has driven the search for materials that combine strength, biocompatibility, and long lifetime. Compared to stainless steel and Co-Cr-based alloys, titanium (Ti) and its alloys are favored for biomedical implants because of their high strength, corrosion resistance, and biocompatibility. This comprehensive review delivers a wide overview of the field of titanium-based biomaterials for orthopedic implants applications, focusing on their types, mechanical and chemical resistance, surface modifications, innovations in fabrication techniques, titanium matrix composites, and machine learning advancements. Titanium alloys of different crystalline phases, including α, near-α, (α + β), β, and shape memory alloys, offer diverse options for orthopedic applications. Strengthening properties, wear, fatigue, and corrosion resistance are crucial factors influencing the performance and reliability of titanium implants. Moreover, this review discussed the challenges to titanium-based biomaterial durability through surface modifications to enhance their biofunction, wear resistance, corrosion resistance, and antibacterial properties. Recent developments in fabrication techniques for titanium-based biomaterials are also discussed. Eventually, this review investigated how machine learning (ML) revolutionized titanium orthopedic implants by providing insights into the behavior of new alloys, aiding in manufacturing optimization, allowing for real-time quality control, and advancing the development of personalized, biocompatible, and reliable implants.

⚠️ This is an automatic machine translation with an accuracy of 90-95%

Translated Description (Arabic)

أدى الطلب المتزايد على زراعة العظام إلى البحث عن المواد التي تجمع بين القوة والتوافق الحيوي والعمر الطويل. بالمقارنة مع الفولاذ المقاوم للصدأ والسبائك القائمة على Co - Cr، يفضل التيتانيوم (Ti) وسبائكه للزراعة الطبية الحيوية بسبب قوتها العالية ومقاومتها للتآكل وتوافقها الحيوي. تقدم هذه المراجعة الشاملة نظرة عامة واسعة على مجال المواد الحيوية القائمة على التيتانيوم لتطبيقات زراعة العظام، مع التركيز على أنواعها، والمقاومة الميكانيكية والكيميائية، وتعديلات السطح، والابتكارات في تقنيات التصنيع، ومركبات مصفوفة التيتانيوم، وتطورات التعلم الآلي. توفر سبائك التيتانيوم ذات المراحل البلورية المختلفة، بما في ذلك α و near - α و (α + β) و β وسبائك ذاكرة الشكل، خيارات متنوعة لتطبيقات جراحة العظام. يعد تقوية الخصائص والتآكل والتعب ومقاومة التآكل من العوامل الحاسمة التي تؤثر على أداء وموثوقية غرسات التيتانيوم. علاوة على ذلك، ناقشت هذه المراجعة التحديات التي تواجه متانة المواد الحيوية القائمة على التيتانيوم من خلال تعديلات السطح لتعزيز وظيفتها الحيوية ومقاومة التآكل ومقاومة التآكل والخصائص المضادة للبكتيريا. كما نوقشت التطورات الأخيرة في تقنيات تصنيع المواد الحيوية القائمة على التيتانيوم. في نهاية المطاف، حققت هذه المراجعة في كيفية قيام التعلم الآلي (ML) بإحداث ثورة في زراعة العظام التيتانيوم من خلال تقديم رؤى حول سلوك السبائك الجديدة، والمساعدة في تحسين التصنيع، والسماح بمراقبة الجودة في الوقت الفعلي، وتعزيز تطوير غرسات شخصية ومتوافقة حيوياً وموثوقة.

Translated Description (French)

La demande croissante d'implants orthopédiques a conduit à la recherche de matériaux alliant résistance, biocompatibilité et longue durée de vie. Par rapport à l'acier inoxydable et aux alliages à base de Co-Cr, le titane (Ti) et ses alliages sont préférés pour les implants biomédicaux en raison de leur haute résistance, de leur résistance à la corrosion et de leur biocompatibilité. Cette revue complète offre un large aperçu du domaine des biomatériaux à base de titane pour les applications d'implants orthopédiques, en se concentrant sur leurs types, leur résistance mécanique et chimique, les modifications de surface, les innovations dans les techniques de fabrication, les composites à matrice de titane et les progrès de l'apprentissage automatique. Les alliages de titane de différentes phases cristallines, y compris les alliages α, near-α, (α + β), β et à mémoire de forme, offrent diverses options pour les applications orthopédiques. Le renforcement des propriétés, l'usure, la fatigue et la résistance à la corrosion sont des facteurs cruciaux qui influencent les performances et la fiabilité des implants en titane. De plus, cette revue a discuté des défis de la durabilité des biomatériaux à base de titane par le biais de modifications de surface pour améliorer leur biofonction, leur résistance à l'usure, leur résistance à la corrosion et leurs propriétés antibactériennes. Les développements récents dans les techniques de fabrication de biomatériaux à base de titane sont également discutés. Finalement, cette revue a étudié comment l'apprentissage automatique (ML) a révolutionné les implants orthopédiques en titane en fournissant des informations sur le comportement de nouveaux alliages, en aidant à l'optimisation de la fabrication, en permettant un contrôle de la qualité en temps réel et en faisant progresser le développement d'implants personnalisés, biocompatibles et fiables.

Translated Description (Spanish)

La creciente demanda de implantes ortopédicos ha impulsado la búsqueda de materiales que combinen resistencia, biocompatibilidad y larga vida útil. En comparación con el acero inoxidable y las aleaciones a base de Co-Cr, el titanio (Ti) y sus aleaciones son los preferidos para los implantes biomédicos debido a su alta resistencia, resistencia a la corrosión y biocompatibilidad. Esta revisión exhaustiva ofrece una amplia visión general del campo de los biomateriales a base de titanio para aplicaciones de implantes ortopédicos, centrándose en sus tipos, resistencia mecánica y química, modificaciones superficiales, innovaciones en técnicas de fabricación, compuestos de matriz de titanio y avances en el aprendizaje automático. Las aleaciones de titanio de diferentes fases cristalinas, incluidas las aleaciones α, casi-α, (α + β), β y con memoria de forma, ofrecen diversas opciones para aplicaciones ortopédicas. Las propiedades de refuerzo, el desgaste, la fatiga y la resistencia a la corrosión son factores cruciales que influyen en el rendimiento y la fiabilidad de los implantes de titanio. Además, esta revisión discutió los desafíos para la durabilidad del biomaterial a base de titanio a través de modificaciones superficiales para mejorar su biofunción, resistencia al desgaste, resistencia a la corrosión y propiedades antibacterianas. También se discuten los desarrollos recientes en las técnicas de fabricación de biomateriales a base de titanio. Finalmente, esta revisión investigó cómo el aprendizaje automático (ML) revolucionó los implantes ortopédicos de titanio al proporcionar información sobre el comportamiento de las nuevas aleaciones, ayudar en la optimización de la fabricación, permitir el control de calidad en tiempo real y avanzar en el desarrollo de implantes personalizados, biocompatibles y confiables.

Additional details

Additional titles

Translated title (Arabic)
سبائك ومركبات أساسها التيتانيوم لزراعة العظام التطبيقات: مراجعة شاملة
Translated title (French)
Alliages et composites à base de titane pour implants orthopédiques Applications : un examen complet
Translated title (Spanish)
Aleaciones y compuestos a base de titanio para implantes ortopédicos Aplicaciones: una revisión exhaustiva

Identifiers

Other
https://openalex.org/W4392768957
DOI
10.1016/j.matdes.2024.112850

GreSIS Basics Section

Is Global South Knowledge
Yes
Country
Egypt

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