Published October 30, 2018 | Version v1
Publication Open

Anatomic and Cellular Niches for <i>Mycobacterium tuberculosis</i> in Latent Tuberculosis Infection

Creators

  • 1. Makerere University
  • 2. Queen Mary University of London
  • 3. Kymab (United Kingdom)

Description

Latent tuberculosis has been recognized for over a century, but discovery of new niches, where Mycobacterium tuberculosis resides, continues. We evaluated literature on M.tuberculosis locations during latency, highlighting that mesenchymal and hematopoietic stem cells harbor organisms in sensitized asymptomatic individuals.

⚠️ This is an automatic machine translation with an accuracy of 90-95%

Translated Description (Arabic)

تم التعرف على السل الكامن لأكثر من قرن من الزمان، ولكن لا يزال اكتشاف منافذ جديدة، حيث توجد المتفطرة السلية. قمنا بتقييم الأدبيات حول مواقع السل أثناء الكمون، مع تسليط الضوء على أن الخلايا الجذعية الوسيطة والمكونة للدم تؤوي كائنات حية في الأفراد الذين لا يعانون من أعراض الحساسية.

Translated Description (French)

La tuberculose latente est reconnue depuis plus d'un siècle, mais la découverte de nouvelles niches, où réside Mycobacterium tuberculosis, se poursuit. Nous avons évalué la littérature sur les localisations de M.tuberculosis pendant la latence, en soulignant que les cellules souches mésenchymateuses et hématopoïétiques hébergent des organismes chez des individus asymptomatiques sensibilisés.

Translated Description (Spanish)

La tuberculosis latente se ha reconocido durante más de un siglo, pero el descubrimiento de nuevos nichos, donde reside Mycobacterium tuberculosis, continúa. Evaluamos la literatura sobre las ubicaciones de M. tuberculosis durante la latencia, destacando que las células madre mesenquimales y hematopoyéticas albergan organismos en individuos asintomáticos sensibilizados.

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Additional details

Additional titles

Translated title (Arabic)
المنافذ التشريحية والخلوية <i>لمرض المتفطرة السلية</i> في عدوى السل الكامنة
Translated title (French)
Niches anatomiques et cellulaires pour <i>Mycobacterium tuberculosis</i> dans l'infection tuberculeuse latente
Translated title (Spanish)
Nichos anatómicos y celulares para <i>Mycobacterium tuberculosis en la</i> infección tuberculosa latente

Identifiers

Other
https://openalex.org/W2904821635
DOI
10.1093/infdis/jiy579

Is supplement to
https://openalex.org/W747133875 (Other)
https://openalex.org/W4308058527 (Other)
https://openalex.org/W4210506554 (Other)
https://openalex.org/W2972094210 (Other)
https://openalex.org/W2412323770 (Other)
https://openalex.org/W2123708792 (Other)
https://openalex.org/W2110949356 (Other)
https://openalex.org/W2051276691 (Other)
https://openalex.org/W2042252940 (Other)
https://openalex.org/W1538374398 (Other)

GreSIS Basics Section

Is Global South Knowledge
Yes
Country
Uganda

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